Discuss the clinical manifestations and underlying pathological alterations in the nervous and vascular systems associated with diabetes mellitus

There are many causes of local neurological and vascular problems within the lower limb which may result in the impairment of wound healing. One of these causes is Diabetes Mellitus.Discuss the clinical manifestations and underlying pathological alterations in the nervous and vascular systems associated with diabetes mellitus.Your assignment should demonstrate your ability to search and appraise the relevant literature in this area.Guidelines for the AssignmentThe word limit for the assignment is 2,000.The amount of words used should be clearly indicated at the end of the assignment.An additional 10% increase on the word limit is allowed therefore the maximum number of words allowed is 2,200.The assignment should be word processed or typed using Ariel Font or Times New Roman size 11 with double spaces between lines.Allocation of MarksMarks will be awarded for, A clear and logical structure to the work. A clear search strategy. Correct response to the question asked. Ability to discuss and examine the question asked as opposed to presenting factual information from text books or other sources. Use of relevant reading to support statements with correct use of references. Relevant reading will be published articles, relevant text books, clinical guidelines and the BNF.