Write a research paper on the Colorimetric principle of detection, utilised by Nanobiosensors,and explain the science behind the Principle.

Write a research paper on the Colorimetric principle of detection, utilised by Nanobiosensors,and explain the science behind the Principle. Discuss an example of a nano-biosensor which utilises this detection principle. How is it different from conventional non-nano methods? Give advantages and disadvantages. How could this sensor be mass-produced? Give details of the fabrication method. Is it going to be cost-effective?